产品货号：
Z23818
中文名称：
POU2AF1抗体
英文名称：
Anti-POU2AF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-POU2AF1 Antibody |
| 指标别名 | POU class 2 homeobox associating factor 1;BOB1;OBF-1;OBF1;OCAB;POU2AF1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | POU2AF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of mouse BOB1(238-256aa EEEESNTYELNHTLSVEGF),different from the related rat sequence by one amino acid,and from human sequence by four amino acids. |
| 实际分子量 | 35KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | POU2AF1(POU domain class 2-associating factor 1),also known as OBF1,BOB1 and OCAB,is a protein that in humans is encoded by the POU2AF1 gene.POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA.The versatility of POU protein operation is additionally conferred at the dimerization level.Casellas et al.(2002) reported that OCAB is essential for V(D)J recombination of a subset of Ig-kappa genes.They showed that OCAB modulates recombination by directly enhancing Ig-kappa gene transcription in vivo.Siegel et al.(2006) suggested that,together with dysregulation of other OCAB target genes,altered regulation of SYK may help explain the magnitude of defects observed in B-cell development,including the pre-B1-to-pre-B2 transition,and immune responses in Ocab -/- mice. |
| Uniprot ID | Q64693 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | POU class 2 associating factor 1 |
| 蛋白名全称 | POU domain class 2-associating factor 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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